• ZIKV ZIKV-E recombinant protein (C-human IgG1-Fc)

ZIKV ZIKV-E recombinant protein (C-human IgG1-Fc)

Cat.#: 514831

Size:

Special Price 621.5 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    ZIKV ZIKV-E recombinant protein (C-human IgG1-Fc)
  • Documents
  • Description
    Envelope of Zika virus is resposible for receptor binding and membrane. Analysis of the envelope protein of Zika, from Brazilian Zika SPH2015 (KU321639), indicates predicted B and T cell epitopes in peptides that are consistent to those reported for dengue, YFYF and Japanese encephalitis.The envelope Domain II B cell epitope, to which much dengue non-neutralizing cross reaction is attributed, is also conserved also in Zika virus, consistent with prior field observations of cross reactivity with dengue and YF. Domain III of the Zika envelope protein, likely the main specific neutralizing domain, is distinct from recent Brazilian dengue isolates and a recent Peruvian YF isolate (GQ379163), 76% of possible major histocompatibility complex class (MHC) I and MHC II binding peptides and potential B cell linear epitopes are unique to Zika virus.
  • Uniprot ID
    ALU33341.1
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the Zika virus (strain Zika SPH2015) E / Envelope (domain III) (ALU33341.1) (Val593-Lys699) was expressed with the Fc region of human IgG1 at the C-terminus.
  • Protein Species
    ZIKV
  • Molecular weight
    The recombinant Zika virus (strain Zika SPH2015) E / Envelope (domain III) consists of 345 amino acids and predicts a molecular mass of 38.2 kDa.
  • Purity
    > 90 % as determined by SDS-PAGE.
  • Validations

    ZIKV Envelope / Zika-E Protein 14764

    ZIKV Envelope / Zika-E Protein 14764

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"