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Product Name
XBP1 antibody
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Description
XBP1 Rabbit Polyclonal antibody. Positive WB detected in rat spleen tissue, mouse spleen tissue. Observed molecular weight by Western-blot: 32 kDa
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Tested applications
ELISA, WB
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Species reactivity
Human, Mouse, Rat; other species not tested.
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Alternative names
TREB5 antibody; X box binding protein 1 antibody; XBP 1 antibody; XBP1 antibody; XBP2 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of XBP1 recombinant protein (Accession Number: NM_005080). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:1000
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Validations
rat spleen tissue were subjected to SDS PAGE followed by western blot with Catalog No:116981(XBP1 Antibody) at dilution of 1:300
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Background
X-box-binding protein 1 (XBP1), also named as TREB5, is a 261 amino acid protein, which contains one bZIP domain and belongs to the bZIP family. XBP1 localizes in the nucleus and as a transcription factor is essential for hepatocyte growth, the differentiation of plasma cells, the immunoglobulin secretion, and the unfolded protein response. XBP1 has an association with major affective disorder. The molecular weight of protein generated from the spliced XBP1 mRNA is 54 kDa and protein generated from unspliced Xbp1 mRNA is 33 kDa.
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