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Product Name
Mouse Vitronectin (His Tag) recombinant protein
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Description
Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.
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Protein name
Vitronectin
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Protein short names
V75; VITRONECTIN; VTN; VN; RP23-399H5.3; VNT; AI256434
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Uniprot ID
P29788
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Gene Name
Vtn
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the mouse vitronectin (NP_035837.1) (Met 1-Lys 478) was expressed, with a polyhistidine tag at the C-terminus.
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Protein Species
Mouse
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Molecular weight
The secreted recombinant mouse vitronectin consists of 470 amino acids and has a predicted molecular mass of 54.2 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rmvitronectin is approximately 75-85 kDa due to glycosylation.
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Purity
> 94 % as determined by SDS-PAGE
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Activity
Measured by the ability of the immobilized protein to support the adhesion of DU145 human prostate carcinoma cells.
When cells are added to mouse Vitronectin coated plates (10 μg/mL and 100 μL/well), > 60% cells will adhere specifically after 30 minutes at 37 ℃. -
Validations
Mouse Vitronectin / VTN Protein (His Tag) SDS-PAGE
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