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Product Name
Human LMAN2L (Fc Tag) recombinant protein
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Description
LMAN2L contains 1 L-type lectin-like domain and is expressed in numerous tissues. It is highly expressed in skeletal muscle and kidney, and its intermediate expression levels in heart, liver and placenta, low levels in brain, thymus, spleen, small intestine and lung. LMAN2L may be involved in the regulation of export from the endoplasmic reticulum of a subset of glycoproteins. It also may function as a regulator of ERGIC-53. LMAN2L gene may be modulated by acetylation; phosphorylation, as detailed at PhosphoSite. Alternative splicing produces 2 isoforms of the human protein. LMAN2L localize in various compartments.
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Protein name
VIP36-like protein
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Protein short names
VIP36-LIKE; A630028F14RIK; VIPL; VIP36-LIKE PROTEIN; LMAN2-LIKE PROTEIN; PSEC0028
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Uniprot ID
Q9H0V9
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Gene Name
LMAN2L; VIPL; PSEC0028; UNQ368/PRO704
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human LMAN2L (NP_110432.1) (Met1-Ala304) was expressed with the Fc region of human IgG1 at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human LMAN2L/Fc is a disulfide-linked homodimer. The reduced monomer comprises 501 amino acids and has a predicted molecular mass of 56.9 kDa. The apparent molecular mass of the protein is approximately 63 kDa in SDS-PAGE under reducing conditions.
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Purity
> 80 % as determined by SDS-PAGE
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Validations
Human LMAN2L Protein (Fc Tag) SDS-PAGE
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