Human VSIG2/CTXL (His Tag) recombinant protein

Human VSIG2/CTXL (His Tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

V-set and immunoglobulin domain-containing protein 2, also known as cortical thymocyte-like protein, CT-like protein and VSIG2, is a single-pass type I membrane protein which contains one Ig-like C2-type (immunoglobulin-like) domain and one Ig-like V-type (immunoglobulin-like) domain. VSIG2 is highly expressed in stomach, colon, prostate, trachea and thyroid glands and weakly in bladder and lung. V-set domains are Ig-like domains resembling the antibody variable domain. V-set domains are found in diverse protein families, including immunoglobulin light and heavy chains; in several T-cell receptors such as CD2 (Cluster of Differentiation 2), CD4, CD80, and CD86; in myelin membrane adhesion molecules; in junction adhesion molecules (JAM); in tyrosine-protein kinase receptors; and in the programmed cell death protein 1 (PD1).

V-set and immunoglobulin domain-containing protein 2

UNQ2770/PRO7154; 2210413P10RIK; MGC117653; CTXL; 1190004B15RIK; CTM; AU040484; CTH; VSIG2; CTX

Q96IQ7

VSIG2; CTH; CTXL; UNQ2770/PRO7154

Human Cells

A DNA sequence encoding the human VSIG2 isoform 1 (Q96IQ7-1) extracellular domain (Met 1-Ala 243) was fused with a polyhistidine tag at the C-terminus.

Human

The secreted recombinant human VSIG2 consists of 231 amino acids and has a calculated molecular mass of 24.6 kDa. The apparent molecular mass of rhVSIG2 is approximately 30-35 kDa in SDS-PAGE under reducing conditions due to glycosylation.

> 95 % as determined by SDS-PAGE

Measured by the ability of the immobilized protein to support the adhesion of the HUVEC human umbilical vein endothelial cell line. When 4 x 10E4 cells/well are added to human VSIG2 coated plates (30 μg/ml, 100 μl/well), approximately 25 %-50 % will adhere after one hour at 37 ℃.