-
Product Name
USP22 Polyclonal Antibody
- Documents
-
Description
Polyclonal antibody to USP22
-
Tested applications
WB, IHC
-
Species reactivity
Human
-
Alternative names
USP22 antibody; USP3L antibody; ubiquitin specific peptidase 22 antibody
-
Isotype
Rabbit IgG
-
Preparation
Antigen: Recombinant protein of human USP22
-
Clonality
Polyclonal
-
Formulation
PBS with 0.02% sodium azide, pH7.3.
-
Storage instructions
Store at 4℃. Avoid freeze / thaw cycles.
-
Applications
WB 1:500 - 1:1000
IHC 1:50 - 1:100 -
Validations
Western blot - USP22 Polyclonal Antibody
Western blot analysis of extracts of Jurkat cells, using USP22 antibody .Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.
-
Background
Histone deubiquitinating component of the transcription regulatory histone acetylation (HAT) complex SAGA. Catalyzes the deubiquitination of both histones H2A and H2B, thereby acting as a coactivator. Recruited to specific gene promoters by activators such as MYC, where it is required for transcription. Required for nuclear receptor-mediated transactivation and cell cycle progression.
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"