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Product Name
Cynomolgus IGFBP5 / IGFBP-5 (His Tag) recombinant protein
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Protein name
Uncharacterized protein
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Protein short names
IGFBP-5; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 5; IBP-5; IGF-BINDING PROTEIN 5; IBP5; IGFBP5; AW208790; IGFBP-5P; AI256729
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Uniprot ID
F1PEQ5
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Gene Name
IGFBP5
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the cynomolgus IGFBP5 (F1PEQ5) (Met1-Glu271) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Cynomolgus
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Molecular weight
The recombinant cynomolgus IGFBP5 comprises 263 amino acids and has a calculated molecular mass of 30 KDa. The apparent molecular mass of it is approximately 38 and 23 KDa in SDS-PAGE under reducing conditions.
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Purity
(82+11) % as determined by SDS-PAGE
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Activity
Measured by its ability to inhibit the biological activity of IGFI or IGFII on MCF7 human breast adenocarcinoma cells (Karey, K.P. et al. (1988) Cancer Research 48:4083.).
The ED50 for this effect is typically 0.1-0.5 μg/mL in the presence of 14 ng/mL human IGFII. -
Validations
Cynomolgus IGFBP5 / IGFBP-5 Protein (His Tag) SDS-PAGE
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