Cart 2

Human UBE2A/HHR6A (His Tag) recombinant protein

Cat.#: 502993

Size:

Special Price 442.8 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Human UBE2A/HHR6A (His Tag) recombinant protein
  • Documents
  • Description
    Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In association with the E3 enzyme BRE1 (RNF20 and/or RNF40), it plays a role in transcription regulation by catalyzing the monoubiquitination of histone H2B at 'Lys-120' to form H2BK120ub1. H2BK120ub1 gives a specific tag for epigenetic transcriptional activation, elongation by RNA polymerase II, telomeric silencing, and is also a prerequisite for H3K4me and H3K79me formation. In vitro catalyzes 'Lys-11', as well as 'Lys-48'-linked polyubiquitination. Required for postreplication repair of UV-damaged DNA.
  • Protein name
    Ubiquitin-conjugating enzyme E2 A
  • Protein short names
    RAD6A; HR6A; MRXS30; MHR6A; MRXSN; RP23-286I5.4; UBC2; HHR6A
  • Uniprot ID
    P49459
  • Gene Name
    UBE2A; RAD6A
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the mature form of human UBE2A (P49459) (Met 1-Cys 152) was expressed, with a polyhistidine tag at the N-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human UBE2A consisting of 167 amino acids and has a calculated molecular mass of 19.2 kDa. It migrates as an approximately 18.5 kDa band in SDS-PAGE under reducing conditions.
  • Purity
    > 80 % as determined by SDS-PAGE
  • Validations

    Human UBE2A / HHR6A Protein (His Tag) SDS-PAGE

    Human UBE2A / HHR6A Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"