-
Product Name
Mouse BAFFR / TNFRSF13C / CD268 (Fc Tag) recombinant protein
- Documents
-
Description
B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response.
-
Protein name
Tumor necrosis factor receptor superfamily member 13C
-
Protein short names
LVIS22; BCMD-1; BCMD1; 2010006P15RIK; MGC138235; BAFFR; TNFRSF13C; PROLIXIN; MGC123890; CD268; BCMD; BAFF-R; BROMIX; CTA-250D10.7; CVID4; MGC123891
-
Uniprot ID
Q9D8D0
-
Gene Name
Tnfrsf13c; Baffr; Bcmd; Br3
-
Source/Expression Host
Human Cells
-
Expression Plasmid/cDNA
A DNA sequence encoding the mouse BAFFR (Q9D8D0-1) extracellular domain (Met 1-Ala 71) was fused with the Fc region of human IgG1 at the C-terminus.
-
Protein Species
Mouse
-
Molecular weight
The secreted recombinant mouse BAFFR/Fc is a disulfide-linked homodimeric protein. The reduced monomer comprises 303 amino acids and has a predicted molecular mass of 33.7 kDa. As a result of glycosylation, the apparent molecular mass of rm BAFFR/Fc monomer is approximately 40-45 kDa in SDS-PAGE under reducing conditions.
-
Purity
> 90 % as determined by SDS-PAGE
-
Activity
Immobilized human BAFF (Cat:503353) at 10 μg/ml (100 μl/well) can bind mouse BAFFR-Fc, The EC50 of mouse BAFFR-Fc is 0.14-0.32 μg/ml.
-
Validations
Mouse BAFFR / TNFRSF13C / CD268 Protein (Fc Tag) SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"