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Product Name
Human TNFAIP8/SCC-S2 (His Tag) recombinant protein
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Description
Acts as a negative mediator of apoptosis and may play a role in tumor progression. Suppresses the TNF-mediated apoptosis by inhibiting caspase-8 activity but not the processing of procaspase-8, subsequently resulting in inhibition of BID cleavage and caspase-3 activation.
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Protein name
Tumor necrosis factor alpha-induced protein 8
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Protein short names
SSC-2; NF-KAPPA-B-INDUCIBLE DED-CONTAINING PROTEIN; GG2-1; GM10539; HEAD AND NECK TUMOR AND METASTASIS-RELATED PROTEIN; SCC-S2; TUMOR NECROSIS FACTOR ALPHA-INDUCED PROTEIN 8; AA987150; TNF-INDUCED PROTEIN; ALPHA-INDUCED PROTEIN 8; TNF ALPHA-INDUCED PROTEIN 8; SCCS2; ENSMUSG00000073567; TNF-INDUCED PROTEIN GG2-1; TNFAIP8; TUMOR NECROSIS FACTOR; NDED; E130304C20RIK; MDC-3.13
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Uniprot ID
O95379
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Gene Name
TNFAIP8
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
A DNA sequence encoding the mature form of human TNFAIP8 (O95379) (Met1-Ile198) was expressed with a polyhistide tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human TNFAIP8 consists of 213 amino acids and predicts a molecular mass of 24.8 KDa. It migrates as an approximately 26 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human TNFAIP8 Protein (His Tag) SDS-PAGE
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