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TSPAN3 antibody

Cat.#: 107647

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Special Price 239.0 USD

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Product Information

  • Product Name
    TSPAN3 antibody
  • Documents
  • Description
    TSPAN3 Mouse Monoclonal antibody. Positive WB detected in Hela cells, human blood tissue. Positive FC detected in HeLa cells. Observed molecular weight by Western-blot: 28 kDa
  • Tested applications
    ELISA, WB, FC
  • Species reactivity
    Human, Mouse; other species not tested.
  • Alternative names
    tetraspanin 3 antibody; Tetraspanin TM4 A antibody; TM4 A antibody; TM4SF8 antibody; TSPAN 3 antibody; TSPAN3 antibody
  • Isotype
    Mouse IgG2b
  • Preparation
    This antibody was obtained by immunization of TSPAN3 recombinant protein (Accession Number: NM_005724). Purification method: Caprylic Acid/Ammonium Sulfate Precipitation.
  • Clonality
    Monoclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

  • Validations

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:107647(TSPAN3 antibody) at dilution of 1:1000

    HeLa cells were subjected to SDS PAGE followed by western blot with Catalog No:107647(TSPAN3 antibody) at dilution of 1:1000

    1X10^6 HeLa cells were stained with 0.2ug TSPAN3 antibody (Catalog No:107647, red) and control antibody (blue). Fixed with 90% MeOH blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Mouse IgG(H+L) with dilution 1:1000.

    1X10^6 HeLa cells were stained with 0.2ug TSPAN3 antibody (Catalog No:107647, red) and control antibody (blue). Fixed with 90% MeOH blocked with 3% BSA (30 min). Alexa Fluor 488-congugated AffiniPure Goat Anti-Mouse IgG(H+L) with dilution 1:1000.

  • Background
    Tetraspanin-3 (TSPAN3, also known as TM4SF8) is a member of the tetraspanin (TM4SF) family. Tetraspanins, so named because they contain four transmembrane domains, are frequently expressed at the cell surface in association with each other and with other molecules, and they function to regulate cell adhesion, migration, proliferation, and differentiation. TSPAN3 regulates the proliferation and migration of oligodendrocytes, a process essential for normal myelination and repair.
  • References
    • Thiede-Stan NK, Tews B, Albrecht D, Ristic Z, Ewers H, Schwab ME. Tetraspanin-3 is an organizer of the multi-subunit Nogo-A signaling complex. Journal of cell science. 128(19):3583-96. 2015.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"