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Product Name
TSPAN12 antibody
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Description
TSPAN12 Rabbit Polyclonal antibody. Positive WB detected in HepG2 cells, MCF7 cells. Observed molecular weight by Western-blot: 28kd
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Tested applications
ELISA, WB
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
NET 2 antibody; NET2 antibody; Tetraspan NET 2 antibody; tetraspanin 12 antibody; TM4SF12 antibody; Tspan 12 antibody; TSPAN12 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of TSPAN12 recombinant protein (Accession Number: XM_005250239). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
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Validations
HepG2 cells were subjected to SDS PAGE followed by western blot with Catalog No:116443(TSPAN12 antibody) at dilution of 1:500
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Background
TSPAN12 is a membrane protein of the tetraspanin superfamily, which are characterized by the presence of four conserved transmembrane regions. Tetraspanins have been involved in diverse processes such as cell activation and proliferation, adhesion and motility, differentiation, and cancer. TSPAN12 regulates retinal vascular development by promoting Norrin/beta-catenin signaling (PMID: 19837033 ). Mutations in TSPAN12 are a relatively frequent cause of familial exudative vitreoretinopathy (FEVR) (PMID: 20159111).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"