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Product Name
TSPAN10 antibody
- Documents
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Description
TSPAN10 Rabbit Polyclonal antibody. Positive IF detected in hTERT-RPE1 cells. Positive WB detected in Transfected HEK-293 cells.
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Tested applications
ELISA, IF, WB
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Species reactivity
Human; other species not tested.
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Alternative names
FLJ39607 antibody; OCSP antibody; OCulospanin antibody; tetraspanin 10 antibody; Tspan 10 antibody; TSPAN10 antibody
- Immunogen
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of TSPAN10 recombinant protein (Accession Number: NM_031945). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
IF: 1:20-1:200
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Validations
IF result (nuclear and the base of cilia stain) of anti-TSPAN10 (Catalog No:116441, 1:50) with human hTERT-RPE1 (MeOH fixation) cells by Dr. Moshe Kim.
Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:116441(TSPAN10 Antibody) at dilution of 1:1000
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Background
TSPAN10 is a membrane protein of the tetraspanin superfamily, which are characterized by the presence of four conserved transmembrane regions. Tetraspanins have been involved in diverse processes such as cell activation and proliferation, adhesion and motility, differentiation, and cancer. TSPAN10 belongs to the TSPANC8 subfamily, which also include TSPAN5, TSPAN14, TSPAN15, TSPAN17, and TSPAN33. It has been reported that TSPANC8 tetraspanins interact with ADAM10 and have a conserved function in the regulation of ADAM10 trafficking and activity, thereby positively regulating Notch receptor activation (PMID: 23091066; 23035126).
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