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Product Name
TSHR Polyclonal Antibody
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Description
Polyclonal antibody to TSHR
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Tested applications
WB, IHC
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Species reactivity
Human, Mouse, Rat
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Alternative names
TSHR antibody; CHNG1 antibody; LGR3 antibody; hTSHR-I antibody; thyrotropin receptor antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 21-253 of human TSHR (NP_001018046.1).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
IHC 1:50 - 1:200 -
Validations
Western blot - TSHR Polyclonal Antibody
Western blot analysis of extracts of various cell lines, using TSHR antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 90s.
Immunohistochemistry - TSHR Polyclonal Antibody
Immunohistochemistry of paraffin-embedded rat brain using TSHR Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - TSHR Polyclonal Antibody
Immunohistochemistry of paraffin-embedded rat brain using TSHR Antibody at dilution of 1:100 (40x lens).
Immunohistochemistry - TSHR Polyclonal Antibody
Immunohistochemistry of paraffin-embedded mouse brain using TSHR Antibody at dilution of 1:100 (40x lens).
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Background
Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism (By similarity).
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"