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Product Name
TRIP4 antibody
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Description
TRIP4 Rabbit Polyclonal antibody. Positive WB detected in HL-60 cells, COLO 320 cells, HeLa cells. Observed molecular weight by Western-blot: 60-65kd
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Tested applications
ELISA, WB
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Species reactivity
human, mouse, rat; other species not tested.
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Alternative names
TRIP4 antibody; TRIP 4 antibody; TR interacting protein 4 antibody; ASC 1 antibody; HsT17391 antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of TRIP4 recombinant protein (Accession Number: NM_016213). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:500-1:5000
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Validations
HL-60 cells were subjected to SDS PAGE followed by western blot with Catalog No:116390(TRIP4 antibody) at dilution of 1:1000
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Background
Thyroid hormone receptor interactor 4(TRIP4), other named ASC1, is a transcriptional coactivator that promote transcriptional efficiencies. It harbors an autonomous transactivation domain that contains a putative zinc finger motif, which serves as a binding site for nuclear receptors for thyroid, estrogen, all-trans-retinoic acid and RXR by interaction with SRC-1 or CBP/p300. There are two forms of ASC1 have been detected in mRNA level, isoform1(581aa, ~65kd) and isoform2(539aa,~60kd)(12077347,12390891)
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