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Product Name
Human TMEM25 (His Tag) recombinant protein
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Description
TMEM25 is a novel member of the immunoglobulin superfamily. Immunoglobulin superfamily members are implicated in immune responses, growth factor signaling, and cell adhesion. TMEM25 contains 1 Ig-like (immunoglobulin-like) domain and is a target of pharmacogenomics in the field of oncology and regenerative medicine. TMEM25 isoform 1, consisting of exons 1-9, encoded a 366-aa transmembrane protein. TMEM25 isoform 2, consisting of exons 1-4 and 6-9, encoded a 322-aa secreted protein. TMEM25 mRNA was expressed in brain, including cerebellar cortex and hippocampus, as well as in neuroblastoma, brain tumors, and gastric cancer. Human TMEM25 gene was located at the 11q23.3 oncogenomic recombination hotspot around the MLL amplicon and the neuroblastoma deleted region.
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Protein name
Transmembrane protein 25
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Protein short names
TMEM25; TRANSMEMBRANE PROTEIN 25; UNQ2531/PRO6030; AI429491; 0610039J01RIK
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Uniprot ID
Q86YD3
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Gene Name
TMEM25; UNQ2531/PRO6030
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human TMEM25 (AAH51841.1) (Met1-Pro224) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human TMEM25 consists of 209 amino acids and predicts a molecular mass of 22.8 KDa. It migrates as an approximately 43 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Human TMEM25 Protein (His Tag) SDS-PAGE
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