-
Product Name
TMEM25 antibody
- Documents
-
Description
TMEM25 Rabbit Polyclonal antibody. Positive WB detected in mouse liver tissue, mouse brain tissue. Positive IHC detected in human stomach cancer tissue, human liver tissue. Observed molecular weight by Western-blot: 40 kDa
-
Tested applications
ELISA, WB, IHC
-
Species reactivity
Human, Mouse, Rat; other species not tested.
-
Alternative names
FLJ14399 antibody; TMEM25 antibody; transmembrane protein 25 antibody
-
Isotype
Rabbit IgG
-
Preparation
This antibody was obtained by immunization of TMEM25 recombinant protein (Accession Number: XM_024448724). Purification method: Antigen affinity purified.
-
Clonality
Polyclonal
-
Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
-
Storage instructions
Store at -20℃. DO NOT ALIQUOT
-
Applications
Recommended Dilution:
WB: 1:500-1:5000
IHC: 1:20-1:200
-
Validations
mouse liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:116181(TMEM25 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach cancer slide using Catalog No:116181(TMEM25 Antibody) at dilution of 1:50
-
Background
TMEM25 is a novel member of the immunoglobulin superfamily. BC042896 and AY358919 cDNAs are derived from human TMEM25 gene. TMEM25 isoform 1 (BC042896), consisting of exons 1-9, encodes a 366-aa transmembrane protein. TMEM25 isoform 2 (AY358919), consisting of exons 1-4 and 6-9, encodes a 322-aa secreted protein (PMID:15254712). Human TMEM25 gene are found to encode transmembrane-type as well as secreted-type proteins due to alternative splicing of exon-skipping type. TMEM25 mRNA is expressed in brain, including cerebellar cortex and hippocampus, as well as in neuroblastoma, brain tumors, and gastric cancer. TMEM25 is a target of pharmacogenomics in the field of oncology and regenerative medicine. TMEM25 mRNAs may be useful members of a panel of favorable prognostic and predictive markers for breast cancer( PMID:19776672).
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"