TMEM25 antibody

Cat.#: 116181

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Product Information

  • Product Name
    TMEM25 antibody
  • Documents
  • Description
    TMEM25 Rabbit Polyclonal antibody. Positive WB detected in mouse liver tissue, mouse brain tissue. Positive IHC detected in human stomach cancer tissue, human liver tissue. Observed molecular weight by Western-blot: 40 kDa
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human, Mouse, Rat; other species not tested.
  • Alternative names
    FLJ14399 antibody; TMEM25 antibody; transmembrane protein 25 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of TMEM25 recombinant protein (Accession Number: XM_024448724). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    mouse liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:116181(TMEM25 Antibody) at dilution of 1:1000

    mouse liver tissue were subjected to SDS PAGE followed by western blot with Catalog No:116181(TMEM25 Antibody) at dilution of 1:1000

    Immunohistochemistry of paraffin-embedded human stomach cancer slide using Catalog No:116181(TMEM25 Antibody) at dilution of 1:50

    Immunohistochemistry of paraffin-embedded human stomach cancer slide using Catalog No:116181(TMEM25 Antibody) at dilution of 1:50

  • Background
    TMEM25 is a novel member of the immunoglobulin superfamily. BC042896 and AY358919 cDNAs are derived from human TMEM25 gene. TMEM25 isoform 1 (BC042896), consisting of exons 1-9, encodes a 366-aa transmembrane protein. TMEM25 isoform 2 (AY358919), consisting of exons 1-4 and 6-9, encodes a 322-aa secreted protein (PMID:15254712). Human TMEM25 gene are found to encode transmembrane-type as well as secreted-type proteins due to alternative splicing of exon-skipping type. TMEM25 mRNA is expressed in brain, including cerebellar cortex and hippocampus, as well as in neuroblastoma, brain tumors, and gastric cancer. TMEM25 is a target of pharmacogenomics in the field of oncology and regenerative medicine. TMEM25 mRNAs may be useful members of a panel of favorable prognostic and predictive markers for breast cancer( PMID:19776672).

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