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Product Name
Recombinant TM204 protein (His tag)
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Description
Recombinant Human Transmembrane protein 204 (TMEM204) Fragment (aa 27-103) - A high-quality, soluble protein fragment ideal for studying cell-cell adhesion mechanisms and paracellular permeability regulation. This 77-amino acid fragment represents a stable, structurally optimized region of the Claudin-like protein 24, specifically designed for structural biology and biochemical applications.
Transmembrane protein 204 (TMEM204), also known as Claudin-like protein 24, is a multi-pass membrane protein that plays a crucial role in regulating paracellular permeability and participates in cell-cell interactions through adherens junctions. The protein localizes to cell junctions and the cell membrane, where it colocalizes with beta-catenin in adherens complexes. This strategic positioning enables TMEM204 to contribute to intercellular communication and barrier function maintenance. The full-length protein's involvement in these fundamental cellular processes makes it an important target for research in epit
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Protein name
Transmembrane protein 204
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Uniprot ID
Q9BSN7
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Gene Name
TMEM204; C16orf30; CLP24
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 27-103 aa (Q9BSN7) were fused with C-terminal 6His tag.
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Sequence
MNHKVGGSTS NWVCQTLEDG RRRSVGLWRS CWLVDRTRGG PSPGARAGQV DAHDCEALGW GSEAAGFQES RGTVKLQFDM MRACNLEHHH HHH
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 10.35 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 10 kDa band.
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Purity
>90%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Validations
Recombinant TM204 protein (His tag) SDS-PAGE
M: Marker; Lane 1: TM204; Lane 2: BSA
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"