Thyroglobulin antibody

Cat.#: 116117

Size:

Special Price 239.0 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Thyroglobulin antibody
  • Documents
  • Description
    Thyroglobulin Rabbit Polyclonal antibody. Positive IHC detected in human thyroid tissue, human thyroid cancer tissue. Positive WB detected in Transfected HEK-293 cells.
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human; other species not tested.
  • Alternative names
    AITD3 antibody; TGN antibody; thyroglobulin antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of Thyroglobulin recombinant protein (Accession Number: NM_003235). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:50-1:500

  • Validations

    Immunohistochemistry of paraffin-embedded human thyroid tissue slide using Catalog No:116117(TG Antibody) at dilution of 1:200 (under 10x lens).

    Immunohistochemistry of paraffin-embedded human thyroid tissue slide using Catalog No:116117(TG Antibody) at dilution of 1:200 (under 10x lens).

    Immunohistochemistry of paraffin-embedded human thyroid tissue slide using Catalog No:116117(TG Antibody) at dilution of 1:200 (under 40x lens).

    Immunohistochemistry of paraffin-embedded human thyroid tissue slide using Catalog No:116117(TG Antibody) at dilution of 1:200 (under 40x lens).

    Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:116117(TG Antibody) at dilution of 1:1000

    Transfected HEK-293 cells were subjected to SDS PAGE followed by western blot with Catalog No:116117(TG Antibody) at dilution of 1:1000

  • Background
    Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"