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Product Name
TFPT antibody
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Description
TFPT Rabbit Polyclonal antibody. Positive IHC detected in human tonsillitis tissue, human brain tissue, human liver tissue. Positive WB detected in K-562 cells, HL-60 cells, mouse liver tissue, PC-3 cells. Observed molecular weight by Western-blot: 29 kDa
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Tested applications
ELISA, WB, IHC
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Species reactivity
Human,Mouse,Rat; other species not tested.
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Alternative names
amida antibody; FB1 antibody; INO80 complex subunit F antibody; INO80F antibody; Protein FB1 antibody; TCF3 fusion partner antibody; TFPT antibody
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Isotype
Rabbit IgG
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Preparation
This antibody was obtained by immunization of TFPT recombinant protein (Accession Number: BC001728). Purification method: Antigen affinity purified.
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Clonality
Polyclonal
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Formulation
PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
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Storage instructions
Store at -20℃. DO NOT ALIQUOT
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Applications
Recommended Dilution:
WB: 1:200-1:2000
IHC: 1:20-1:200
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Validations
K-562 cells were subjected to SDS PAGE followed by western blot with Catalog No:116016(TFPT antibody) at dilution of 1:600
Immunohistochemistry of paraffin-embedded human tonsillitis slide using Catalog No:116016(TFPT Antibody) at dilution of 1:50
Immunohistochemistry of paraffin-embedded human tonsillitis slide using Catalog No:116016(TFPT Antibody) at dilution of 1:50
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Background
TFPT/FB1 is one of three fusion partners of the E2A gene. TFPT/FB1 is expressed at low level in a variety of human tissues, including hemopoietic cell lines from different lineages. The function of the putative TFPT/FB1 protein, however, is currently unknown as database sequence comparisons have failed to reveal strong homology with known proteins. The E2A-TFPT/FB1 fusion appears to be a recurrent feature of pre-B ALLs, suggesting that it might have a role in the development and/or progression of leukemogenesis. The gene encoding TFPT/FB1 is localized on 19q13.4.
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