TDIF/CLE41 peptide
Not For Human Use, Lab Use Only.
Cat.#: 319225
Special Price 101.9 USD
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Product Name
TDIF/CLE41 peptide
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Documents
Batch to batch variation of the purity
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Sequence Shortening
H-HEVPSGPNPISN-OH
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Sequence
H-His-Glu-Val-Pro-Ser-Gly-Pro-Asn-Pro-Ile-Ser-Asn-OH
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Length (aa)
12
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Peptide Purity (HPLC)
95.04%
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Molecular Formula
C53H82N16O19
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Molecular Weight
1247.31
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Source
Synthetic
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Form
Powder
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Description
TDIF (tracheary element differentiation inhibitory factor) plays a crucial role in procambial cell maintenance by suppressing their differentiation into xylem cells and promoting their proliferation in Arabidopsis. TDIF regulates procambial stem cell proliferation via WOX4.
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Storage Guidelines
Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
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References
- Guo X, Wang J, Gardner M, Fukuda H, Kondo Y, Etchells JP, Wang X, Mitchum MG. Identification of cyst nematode B-type CLE peptides and modulation of the vascular stem cell pathway for feeding cell formation. PLoS Pathog. 2017 Feb 3;13(2):e1006142. doi: 10.1371/journal.ppat.1006142. PMID: 28158306; PMCID: PMC5319780.
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About TFA salt
Trifluoroacetic acid (TFA) has a significant impact on peptides due to its role in the peptide synthesis process.
TFA is essential for the protonation of peptides that lack basic amino acids such as Arginine (Arg), Histidine (His), and Lysine (Lys), or ones that have blocked N-termini. As a result, peptides often contain TFA salts in the final product.
TFA residues, when present in custom peptides, can cause unpredictable fluctuations in experimental data. At a nanomolar (nM) level, TFA can influence cell experiments, hindering cell growth at low concentrations (as low as 10 nM) and promoting it at higher doses (0.5–7.0 mM). It can also serve as an allosteric regulator on the GlyR of glycine receptors, thereby increasing receptor activity at lower glycine concentrations.
In an in vivo setting, TFA can trifluoroacetylate amino groups in proteins and phospholipids, inducing potentially unwanted antibody responses. Moreover, TFA can impact structure studies as it affects spectrum absorption.
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Molar Concentration Calculator
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Dilution Calculator
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Percent Concentration Calculator
Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)
Related Products / Services
• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.
• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.
• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"