TAX1BP3 antibody

Cat.#: 115859

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Product Information

  • Product Name
    TAX1BP3 antibody
  • Documents
  • Description
    TAX1BP3 Rabbit Polyclonal antibody. Positive WB detected in mouse ovary tissue, A2780 cells. Positive IHC detected in human small intestine tissue, human kidney tissue, human lung cancer tissue. Observed molecular weight by Western-blot: 15-17kd
  • Tested applications
    ELISA, WB, IHC
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    Tax interaction protein 1 antibody; Tax1 binding protein 3 antibody; TAX1BP3 antibody; TIP 1 antibody; TIP1 antibody
  • Immunogen
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of TAX1BP3 recombinant protein (Accession Number: NM_014604). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.1% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:500-1:5000

    IHC: 1:20-1:200

  • Validations

    mouse ovary tissue were subjected to SDS PAGE followed by western blot with Catalog No:115859(TAX1BP3 antibody) at dilution of 1:1000

    mouse ovary tissue were subjected to SDS PAGE followed by western blot with Catalog No:115859(TAX1BP3 antibody) at dilution of 1:1000

    Immunohistochemical of paraffin-embedded human kidney using Catalog No:115859(TAX1BP3 antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemical of paraffin-embedded human kidney using Catalog No:115859(TAX1BP3 antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemical of paraffin-embedded human small intestine using Catalog No:115859(TAX1BP3 antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human small intestine using Catalog No:115859(TAX1BP3 antibody) at dilution of 1:50 (under 10x lens)

    Immunohistochemical of paraffin-embedded human small intestine using Catalog No:115859(TAX1BP3 antibody) at dilution of 1:50 (under 40x lens)

    Immunohistochemical of paraffin-embedded human small intestine using Catalog No:115859(TAX1BP3 antibody) at dilution of 1:50 (under 40x lens)

  • Background
    Tax-interacting protein 1 (TIP-1, also known as Tax1bp3 or glutaminase-interacting protein, GIP) is unique in its simple structure, a single PDZ domain is the only functional and structural unit identified so far in this small PDZ protein (124 amino acids in human and mouse). High level of TIP-1 expression was detected in human invasive breast cancer cells and that is important for tumor cell adhesion, migration and pulmonary metastasis. However, the precise biological effects of TIP-1 and its functional mechanisms have largely remained elusive. Mutation of TAX1BP3 can cause Dilated Cardiomyopathy with Septo-Optic Dysplasia (PMID: 25645515).

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"