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Product Name
Human CD96 (His Tag) recombinant protein
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Description
May be involved in adhesive interactions of activated T and NK cells during the late phase of the immune response. Promotes NK cell-target adhesion by interacting with PVR present on target cells. May function at a time after T and NK cells have penetrated the endothelium using integrins and selectins, when they are actively engaging diseased cells and moving within areas of inflammation.
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Protein name
T-cell surface protein tactile
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Protein short names
CD96; DKFZP667E2122; 1700109I12RIK; MGC22596; TACTILE
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Uniprot ID
P40200
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Gene Name
CD96
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human CD96 isoform 2 (P40200-2) extracellular domain (Met 1-Met 503) was expressed, with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human CD96 consists of 493 amino acids and predictes a molecular mass of 55 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh CD96 is approximately 120-130 kDa due to high glycosylation.
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Purity
> 90 % as determined by SDS-PAGE
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Activity
1. Measured by its ability to bind recombinant mouse PVR in a functional ELISA.
2. Measured by its ability to bind recombinant Human CD155 in a functional ELISA. -
Validations
Human CD96 Protein (His Tag) SDS-PAGE
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