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Product Name
Human STXBP1 (His & GST Tag) recombinant protein
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Description
May participate in the regulation of synaptic vesicle docking and fusion, possibly through interaction with GTP-binding proteins. Essential for neurotransmission and binds syntaxin, a component of the synaptic vesicle fusion machinery probably in a 1:1 ratio. Can interact with syntaxins 1, 2, and 3 but not syntaxin 4. May play a role in determining the specificity of intracellular fusion reactions.
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Protein name
Syntaxin-binding protein 1
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Protein short names
P67; UNC18-1; NSEC1; MMS10-G; RBSEC1; RP11-56D16.3; SXTBP1; AI326233; AI317162; UNC18H; STXBP1; RP23-17P12.13-003; RB-SEC1; MUNC-18A; FLJ37475; N-SEC1; MS10G; UNC18; MUNC18-1
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Uniprot ID
P61764
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Gene Name
STXBP1; UNC18A
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human STXBP1 isoform 1 (P61764-1) (Met 1-Ser 594) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human STXBP1/GST chimera consists of 831 amino acids and has a calculated molecular mass of 95.4 kDa. It migrates as an approximately 80 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 93 % as determined by SDS-PAGE
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Validations
Human STXBP1 / UNC18A Protein (His & GST Tag) SDS-PAGE
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