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Product Name
Human SUSD4 / Sushi domain-containing protein 4 (Fc Tag)
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Description
Acts as complement inhibitor by disrupting the formation of the classical C3 convertase. Isoform 3 inhibits the classical complement pathway, while membrane-bound isoform 1 inhibits deposition of C3b via both the classical and alternative complement pathways.
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Protein name
Sushi domain-containing protein 4
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Protein short names
PRO222; AI848994; E430021N18RIK; N28096; SUSD4; YHGM196; SUSHI DOMAIN CONTAINING 4; SUSHI DOMAIN-CONTAINING PROTEIN 4; RP11-239E10.4
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Uniprot ID
Q5VX71
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Gene Name
SUSD4; UNQ196/PRO222
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human SUSD4 (Q5VX71-3) (Met1-Phe290) was fused with Fc region of mouse IgG at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human SUSD4/mFc is a disulfide-linked homodimer. The reduced monomer comprises 483 amino acids and has a predicted molecular mass of 53.8 kDa. The apparent molecular mass of the protein is approximately 67 in SDS-PAGE under reducing conditions.
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Purity
> 85 % as determined by SDS-PAGE
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Validations
Human SUSD4 / Sushi domain-containing Protein 4 Protein (Fc Tag) SDS-PAGE
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