Human STIM1 (His Tag) recombinant protein

Cat.#: 500174

Size:

Special Price 353.3 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Human STIM1 (His Tag) recombinant protein
  • Documents
  • Description
    Plays a role in mediating store-operated Ca(2+) entry (SOCE), a Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit, TMEM142A/ORAI1.
  • Protein name
    Stromal interaction molecule 1
  • Protein short names
    IMD10; STRMK; GOK; STIM1; D11S4896E; SIM; TAM; TAM1
  • Uniprot ID
    Q13586
  • Gene Name
    STIM1; GOK
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the human STIM1 (NP_003147.2) extracellular domain (Met 1-Asp 213) was expressed, with a polyhistidine tag at the C-terminus.
  • Protein Species
    Human
  • Molecular weight
    The recombinant human STIM1 consists of 202 amino acids and predictes a molecular mass of 23.3 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh STIM1 is approximately 33-38 kDa due to glycosylation.
  • Purity
    > 97 % as determined by SDS-PAGE
  • Validations

    Human STIM1 / GOK Protein (His Tag) SDS-PAGE

    Human STIM1 / GOK Protein (His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"