Cart 2

HCoV CoV Spike glycoprotein (aa 1-760, His Tag)

Cat.#: 500181

Size:

Special Price 800.3 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    HCoV CoV Spike glycoprotein (aa 1-760, His Tag)
  • Documents
  • Description
    S1 attaches the virion to the cell membrane by interacting with cell receptors, initiating the infection.
  • Protein name
    Spike glycoprotein
  • Protein short names
    S glycoprotein
  • Uniprot ID
    Q5MQD0
  • Gene Name
    S; 3
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the N-terminal fragment of human coronavirus (isolate HKU1) spike glycoprotein (YP_173238.1) (Met 1-Arg 760), corresponding to the S1 region, was fused with a polyhistidine tag at the C-terminus.
  • Protein Species
    HCoV
  • Molecular weight
    The secreted recombinant human coronavirus spike glycoprotein (aa 1-760) comprises 756 amino acids with a predicted molecular mass of 85.8 kDa. As a result of high glycosylation, the apparent molecular mass of the recombinant protein is approximately 130-140 kDa in SDS-PAGE under reducing conditions.
  • Purity
    > 90 % as determined by SDS-PAGE
  • Activity
    Measured by its binding ability in a functional ELISA.
    Immobilized Spike-His (aa 1-760) (Cat: 500181) at 10 μg/ml (100 μl/well) can bind biotinylated human ACE2-Fc (Cat: 501568) with a linear range of 0.16-4.0 μg/ml.
  • Validations

    Human coronavirus spike glycoprotein Protein (aa 1-760, His Tag) SDS-PAGE

    Human coronavirus spike glycoprotein Protein (aa 1-760, His Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"