SLC12A5 Polyclonal Antibody

Cat.#: 162671

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Product Information

  • Product Name
    SLC12A5 Polyclonal Antibody
  • Documents
  • Description
    Polyclonal antibody to SLC12A5
  • Tested applications
    WB
  • Species reactivity
    Human, Mouse, Rat
  • Alternative names
    SLC12A5 antibody; EIEE34 antibody; EIG14 antibody; KCC2 antibody; hKCC2 antibody; solute carrier family 12 member 5 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 945-1025 of human SLC12A5 (NP_001128243.1).
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
  • Storage instructions
    Store at -20℃. Avoid freeze / thaw cycles.
  • Applications
    WB 1:200 - 1:2000
  • Validations

    Western blot - SLC12A5 Polyclonal Antibody

    Western blot - SLC12A5 Polyclonal Antibody

    Western blot analysis of extracts of various cell lines, using SLC12A5 antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 60s.

  • Background
    Mediates electroneutral potassium-chloride cotransport in mature neurons and is required for neuronal Cl(-) homeostasis. As major extruder of intracellular chloride, it establishes the low neuronal Cl(-) levels required for chloride influx after binding of GABA-A and glycine to their receptors, with subsequent hyperpolarization and neuronal inhibition (By similarity). Involved in the regulation of dendritic spine formation and maturation.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"