SLC11A2 antibody

Cat.#: 115298

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Product Information

  • Product Name
    SLC11A2 antibody
  • Documents
  • Description
    SLC11A2 Rabbit Polyclonal antibody. Positive WB detected in COLO 320 cells, HEK-293 cells, human brain tissue, human testis tissue, mouse thymus tissue, SH-SY5Y cells. Observed molecular weight by Western-blot: 60-70, 75-100 kDa
  • Tested applications
    ELISA, WB
  • Species reactivity
    Human,Mouse,Rat; other species not tested.
  • Alternative names
    DCT1 antibody; Divalent cation transporter 1 antibody; Divalent metal transporter 1 antibody; DMT 1 antibody; DMT1 antibody; FLJ37416 antibody; NRAMP 2 antibody; NRAMP2 antibody; SLC11A2 antibody
  • Isotype
    Rabbit IgG
  • Preparation
    This antibody was obtained by immunization of SLC11A2 recombinant protein (Accession Number: NM_001174128). Purification method: Antigen affinity purified.
  • Clonality
    Polyclonal
  • Formulation
    PBS with 0.02% sodium azide and 50% glycerol pH 7.3.
  • Storage instructions
    Store at -20℃. DO NOT ALIQUOT
  • Applications

    Recommended Dilution:

    WB: 1:200-1:2000

  • Validations

    COLO 320 cells were subjected to SDS PAGE followed by western blot with Catalog No:115298(SLC11A2 antibody) at dilution of 1:300

    COLO 320 cells were subjected to SDS PAGE followed by western blot with Catalog No:115298(SLC11A2 antibody) at dilution of 1:300

  • Background
    SLC11A2 (also known as DMT1, Nramp2, and DCT1) is a member of the divalent cation transporters that plays a central role in iron homeostasis. SLC11A2 is widely expressed in many tissues including brain, kidney, testis, duodenum and placenta. As a membrane protein, SLC11A2 is localized on the apical membrane of enterocytes as well as in transferrin-cycle endosomes. Four isoforms of SLC11A2 exist due to the alternative splicing. They differ at the NH2 and COOH termini but share a common central domain. A variety of molecular weights of SLC11A2 in western blot analysis, ranging from 50 to 100 kDa, has been reported in different cells and species. The differences in molecular weights may be attributed to the level of glycosylation, proteolysis, or the membrane protein itself. This antibody detected various forms of SLC11A2 of 45-100 kDa.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"