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Product Name
Human PON3 (50 Ser/Asn, His Tag) recombinant protein
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Description
Has low activity towards the organophosphate paraxon and aromatic carboxylic acid esters. Rapidly hydrolyzes lactones such as statin prodrugs (e.g. lovastatin). Hydrolyzes aromatic lactones and 5- or 6-member ring lactones with aliphatic substituents but not simple lactones or those with polar substituents.
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Protein name
Serum paraoxonase/lactonase 3
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Protein short names
AI786302; 2.810004E+26; PARAOXANASE-3; SERUM PARAOXONASE/LACTONASE 3
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Uniprot ID
Q15166
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Gene Name
PON3
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human PON3 (Q15166-1) (Met 1-Leu 354) (50 Ser/Asn) was expressed, with a polyhistidine tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human PON3 consists of 373 amino acids and predicts a molecular mass of 42 kDa. It migrates as an approximately 45 KDa band in SDS-PAGE under reducing conditions.
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Purity
> 85 % as determined by SDS-PAGE
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Validations
Human PON3 / Paraoxonase 3 Protein (50 Ser/Asn, His Tag) SDS-PAGE
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