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Product Name
Human SerpinB6 (His Tag) recombinant protein
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Description
May be involved in the regulation of serine proteinases present in the brain or extravasated from the blood (By similarity). Inhibitor of cathepsin G, kallikrein-8 and thrombin. May play an important role in the inner ear in the protection against leakage of lysosomal content during stress and loss of this protection results in cell death and sensorineural hearing loss.
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Protein name
Serpin B6
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Protein short names
CAP; MSTP057; D330015H01RIK; SERPINB6A; AI876477; DFNB91; SERPINB6; RP23-262J21.1; SPI3; OVALBUMIN; DKFZP686I04222; RP1-90J20.6; PTI; PI6; MGC111370; 4930482L21RIK
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Uniprot ID
P35237
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Gene Name
SERPINB6; PI6; PTI
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human SERPINB6 (AAB30320.1) (Asp 2-Pro 376) was expressed, with a polyhistidine tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human SERPINB6 consists of 394 amino acids and predicts a molecular mass of 44.9 kDa. It migrates as an approximately 43 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human SerpinB6 / PI-6 Protein (His Tag) SDS-PAGE
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