Mouse Transferrin/TF (His Tag) recombinant protein

Mouse Transferrin/TF (His Tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. It is responsible for the transport of iron from sites of absorption and heme degradation to those of storage and utilization. Serum transferrin may also have a further role in stimulating cell proliferation.

Serotransferrin

PRO1557; BETA-1 METAL-BINDING GLOBULIN; SEROTRANSFERRIN; PRO2086; SIDEROPHILIN; DKFZP781D0156; TF; TRANSFERRIN

Q921I1

Tf; Trf

Human Cells

A DNA sequence encoding the mouse TRF (Q921I1) (Met1-His697) was expressed with a C-terminal polyhistidine tag.

Mouse

The recombinant mouse TRF comprises 689 amino acids and has a predicted molecular mass of 76.3 kDa. The apparent molecular mass of the protein is approximately 61-66 kDa in SDS-PAGE under reducing conditions due to glycosylation.

> 95 % as determined by SDS-PAGE

Measured in a serum-free cell proliferation assay using MCF-7 human breast cancer cells. Karey, K.P. et al. (1988) Cancer Research 48:4083.
The ED₅₀ for this effect is typically 0.05-0.2 μg/mL.