-
Product Name
Human STK16/PKL12 (His & NusA Tag) recombinant protein
- Documents
-
Description
Membrane-associated protein kinase that phosphorylates on serine and threonine residues. In vitro substrates include DRG1, ENO1 and EIF4EBP1. Also autophosphorylates. May be involved in secretory vesicle trafficking or intracellular signaling. May have a role in regulating stromal-epithelial interactions that occur during ductal morphogenesis in the mammary gland. May be involved in TGF-beta signaling. Able to autophosphorylate on Tyr residue; it is however unclear whether it has tyrosine-protein kinase toward other proteins.
-
Protein name
Serine/threonine-protein kinase 16
-
Protein short names
TSF-1; STK16; PKL12; MPSK; TSF1; MGC16211; KRCT; FLJ39635; EDPK
-
Uniprot ID
O75716
-
Gene Name
STK16; MPSK1; PKL12; TSF1
-
Source/Expression Host
E. coli
-
Expression Plasmid/cDNA
A DNA sequence encoding the native human STK16 (AAH02618.1) (Met 1-Ile 305) was fused with the polyhistidine-tagged NusA tag at the N-terminus.
-
Protein Species
Human
-
Molecular weight
The recombinant human STK16/NusA chimera consisting of 820 amino acids and has a calculated molecular mass of 92 kDa. It migrates as an 105 kDa band in SDS-PAGE under reducing conditions.
-
Purity
> 85 % as determined by SDS-PAGE
-
Activity
Kinase activity untested
-
Validations
Human STK16 / PKL12 / MPSK Protein (His & NusA Tag) SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"