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Product Name
Human SEMA6A (His Tag) recombinant protein
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Description
Cell surface receptor for PLXNA2 that plays an important role in cell-cell signaling. Required for normal granule cell migration in the developing cerebellum. Promotes reorganization of the actin cytoskeleton and plays an important role in axon guidance in the developing central nervous system. Can act as repulsive axon guidance cue. Has repulsive action towards migrating granular neurons. May play a role in channeling sympathetic axons into the sympathetic chains and controlling the temporal sequence of sympathetic target innervation (By similarity).
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Protein name
Semaphorin-6A
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Protein short names
B2B997CLO; SEMA6A-1; A730020P05RIK; SEMAQ; SEMA; SEMAPHORIN 6A; VIA; KIAA1368; SEMA6A; HT018; AI851735; 93301580000000; SEMA6A1
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Uniprot ID
Q9H2E6
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Gene Name
SEMA6A; KIAA1368; SEMAQ
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human SEMA6A (NP_065847.1) extracellular domain (Met 1-Thr 649) was expressed, with a polyhistidine tag at the C-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human SEMA6A consists of 642 amino acids and predictes a molecular mass of 72.2 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rh SEMA6A is approximately 85-95 kDa due to glycosylation.
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Purity
> 90 % as determined by SDS-PAGE
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Validations
Human Semaphorin 6A / SEMA6A Protein (His Tag) SDS-PAGE
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