• S-PE peptide

S-PE peptide

Not For Human Use, Lab Use Only.

Cat.#: 319151

Size:
Optional Service: TFA RemovalWhat's this?

Special Price 117.7 USD

Availability: 1-2 weeks
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Product Information

  • Product Name
    S-PE peptide
  • Documents
  • Quantity/Unit
    1 Vial
  • Sequence
    Acetylation-PCRFFESHVA-OH
  • Three letter code
    Acetylation-Pro-Cys-Arg-Phe-Phe-Glu-Ser-His-Val-Ala-OH
  • Length (aa)
    10
  • Peptide Purity (HPLC)
    95.43
  • Molecular Formula
    C56H79N15O15S
  • Molecular Weight
    1234.38
  • Source
    Synthetic
  • Additional Information
    S-PE is a peptide(sequence: PCRFFESHVA) with active stem cell recruitment capacity. S-PE was screened and identified on Discovery Studio software through peptide display techniques. S-PE showed a outstanding cell homing effect with bone marrow mesenchymal stem cells (BMSCs), as well as promoted osteogenic differentiation to some extent, since S-PE is a promising target peptides simulating the functional domain of stromal cell-derived factor-1 (SDF-1).
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual:Handling and Storage of Synthetic Peptides
  • References
    • Zhi Peng, Shiwei Niu, Li Gui, Xiaolin Kuang, Fan Li, Bo Chen, Wanting Li, Jianlin Jiao, Sheng Lu, Di Lu, Wnt3a loaded deformable hydrogel acts as a 3D culture platform for in situ recruitment of stem cells to efficiently repair bone defects via the asymmetric division, Chemical Engineering Journal, Volume 442, Part 1, 2022, 136163, ISSN 1385-8947, https://doi.org/10.1016/j.cej.2022.136163.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a strong acid, which is commonly used to cleave synthesized peptides from solid-phase resins and is also used to improve HPLC performance in the peptide purification step. By default, custom peptides are delivered as lyophilized TFA salts, and can contain as much as 10-45% TFA.

    TFA in custom peptides can cause inexplicable discrepancies in subsequent assay data. For instance, TFA in nM concentrations has been shown to interfere with cellular assays, inhibiting cellular proliferation in some instances, and increasing cell viability in others . It has also been found to be an unintended allosteric modulator of the glycine receptor, GlyR.

    TFA Removal Service is recommended for:

    • Peptides that will be used in cellular assays
    • Peptides that will be used as APIs or in manufactured products
    • For hydrophilic peptides containing numerous basic residues

Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"