S.cerevisiae PAM18/TIM14/YLR008C recombinant protein

Cat.#: 518478

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Product Information

  • Product Name
    S.cerevisiae PAM18/TIM14/YLR008C recombinant protein
  • Documents
  • Description
    Mitochondrial import inner membrane translocase subunit TIM14 (TIM14) is an essential component of the PAM complex. PAM complex is required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner. In the complex, TIM14 is required to stimulate activity of mtHSP70 (SSC1). TIM14 belongs to the DnaJ family, which has been involved in Hsp40/Hsp70 chaperone systems. As a mitochondrial chaperone, TIM14 functions as part of the TIM23 complex import motor to facilitate the import of nuclear-encoded proteins into the mitochondria. TIM14 also complexes with prohibitin complexes to regulate mitochondrial morphogenesis, and has been implicated in dilated cardiomyopathy with ataxia.
  • Protein name
    Pam18p(PAM18)
  • Protein short names
    TIM14; YLR008C
  • Uniprot ID
    Q07914
  • Source/Expression Host
    E. coli
  • Expression Plasmid/cDNA
    A DNA sequence encoding the S.cerevisiae PAM18/TIM14/YLR008C Phe99-Lys168 is expressed.
  • Protein Species
    S.cerevisiae
  • Purity
    >95% as determined by SDS-PAGE.
  • Validations

    S.cerevisiae PAM18/TIM14/YLR008C recombinant protein

    S.cerevisiae PAM18/TIM14/YLR008C recombinant protein

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"