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Product Name
Human APAP-1 / AAP1 / RYBP (His & GST Tag) recombinant protein
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Description
Inhibits ubiquitination and subsequent degradation of TP53, and thereby plays a role in regulating transcription of TP53 target genes. May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1. May bind to DNA. Promotes apoptosis.
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Protein name
RING1 and YY1-binding protein
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Protein short names
2410018J24RIK; YEAF1; APAP-1; DED-ASSOCIATED FACTOR; RYBP; RING1 AND YY1 BINDING PROTEIN; DEATH EFFECTOR DOMAIN-ASSOCIATED FACTOR; AAP1; YY1 AND E4TF1 ASSOCIATED FACTOR 1; RING1 INTERACTOR RYBP; DEDAF; APOPTIN-ASSOCIATING PROTEIN 1
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Uniprot ID
Q8N488
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Gene Name
RYBP; DEDAF; YEAF1
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Source/Expression Host
Baculovirus-Insect Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the human RYBP (Q8N488) (Met1-Phe228) was fused with the N-terminal polyhistidine-tagged GST tag at the N-terminus.
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Protein Species
Human
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Molecular weight
The recombinant human RYBP /GST chimera consists of 465 amino acids and has a calculated molecular mass of 52.6 kDa. The recombinant protein migrates as an approximately 58 kDa band in SDS-PAGE under reducing conditions.
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Purity
> 85 % as determined by SDS-PAGE
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Validations
Human APAP-1 / AAP1 / RYBP Protein (His & GST Tag) SDS-PAGE
Related Products / Services
Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"