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Product Name
Rhesus KIM-1/TIM1/HACVR1 (His Tag) recombinant protein
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Description
Human HAV cellular receptor 1 (HAVCR1), also known as Kidney injury molecule 1 (KIM-1) and T cell immunoglobulinmucin 1 (TIM-1), is a type â… integral membrane glycoprotein. KIM-1 protein is widely expressed with highest levels in kidney and testis. It has been shown to play a major role as a human susceptibility gene for asthma, allergy and autoimmunity. IgA1lambda is a specific ligand of KIM-1 protein and that their association has a synergistic effect in virus-receptor interactions. KIM-1 involves in the pathogenesis of acute kidney injury. It had been confirmed that KIM-1 is a human urinary renal dysfunction biomarker. Moreover, KIM-1 protein is a novel regulatory molecule of flow-induced calcium signaling.
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Protein short names
RP23-31K14.2; HAVCR1; KIM1; HAVCR-1; TIMD1; TIM; TIM-1; TIMD-1; KIM-1; CANIS LUPUS FAMILIARIS; AI503787; HAVCR; TIM1
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the rhesus HAVCR1 (BAJ61041.1) N-terminal segment (Asp 20-Val 135) was expressed with an N-terminal polyhistidine tag.
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Protein Species
Rhesus
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Molecular weight
The recombinant rhesus HAVCR1 consists of 135 amino acids and has a calculated molecular mass of 15 kDa.
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Purity
> 95 % as determined by SDS-PAGE
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Validations
Cynomolgus KIM-1 / TIM1 / HACVR1 Protein (His Tag) SDS-PAGE
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