Rhesus EGFR/HER1/ErbB1 (His Tag) recombinant protein

Cat.#: 504880

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Product Information

  • Product Name
    Rhesus EGFR/HER1/ErbB1 (His Tag) recombinant protein
  • Documents
  • Description
    As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands including EGF, amphiregulin, TGF-α, betacellulin, etc. EGFR protein plays a crucial role in signaling pathway in the regulation of cell proliferation, survival and differentiation. Binding of a ligand induces EGFR protein homo- or heterodimerization, the subsequent tyrosine autophosphorylation and initiates various down stream pathways (MAPK, PI3K/PKB and STAT). In addition, EGFR signaling also has been shown to exert action on carcinogenesis and disease progression, and thus EGFR protein is proposed as a target for cancer therapy currently.
  • Protein short names
    MENA; PIG61; HER1; ERBB-1; WA5; 9030024J15RIK; WA2; NISBD2; ERBB1; ERRP; ERBB; ERRB1; RP23-295E4.1; EGFR; WA-2; AI552599
  • Uniprot ID
    A0A0A0MQ66
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the rhesus EGFR (XP_001107305.1) (Met1-Ser645) was expressed with a polyhistidine tag at the C-terminus.
  • Protein Species
    Rhesus
  • Molecular weight
    The recombinant rhesus EGFR consists 632 amino acids and predicts a molecular mass of 70.1 kDa.
  • Purity
    > 85 % as determined by SDS-PAGE
  • Validations

    Rhesus EGFR / HER1 / ErbB1 Protein (His Tag)

    Rhesus EGFR / HER1 / ErbB1 Protein (His Tag)

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"