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Product Name
Rat RCN3 (His Tag) recombinant protein
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Description
RCN3 belongs to the CREC family which contains multiple EF-hand Ca2+-binding proteins localized to the secretory pathway. RCN3 sequence is characterized by the presence of five Arg-Xaa-Xaa-Arg motifs, which represents the target sequence of subtilisin-like proprotein convertases(SPCs). SPCs are a family of seven structurally related serine endoproteases that are involved in the proteolytic activation of proproteins.RCN3 is transiently associated with proPACE4, but not with mature PACE4. Inhibition of PACE4 maturation by a Ca2+ ionophore resulted in accumulation of the proPACE4-RCN-3 complex in cells. It has been proposed that elective and transient association of RCN3 with the precursor of PACE4 plays an important role in the biosynthesis of PACE4.
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Protein short names
RLP49; EF-HAND CALCIUM-BINDING PROTEIN RLP49; UNQ239/PRO272; 6030455P07RIK; RETICULOCABIN; D530026G20RIK; RETICULOCALBIN-3; D7ERTD671E
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the rat Rcn3 (Met1-His324) was expressed with a polyhistidine tag at the C-terminus.
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Protein Species
Rat
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Molecular weight
The recombinant rat Rcn3 consists 315 amino acids and predicts a molecular mass of 36.4 kDa.
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Purity
> 90 % as determined by SDS-PAGE.
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Validations
Rat RCN3 Protein (His Tag)
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