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Product Name
Rat Csf1/Csfm recombinant protein
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Description
Rat Macrophage colony-stimulating factor 1(MCSF,CSF1) is a single-pass type I membrane cytokine. It is a hematopoietic growth factor that plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes, such as macrophages and monocytes. MCSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It is involved in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development which for normal male and female fertility. It promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration. MCSF also plays a role in lipoprotein clearance.
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Protein name
colony stimulating factor 1(Csf1)
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Protein short names
Csfm
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Uniprot ID
Q8JZQ0
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Source/Expression Host
Human Cells
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Expression Plasmid/cDNA
A DNA sequence encoding the Rat Csf1/Csfm Gln33-Arg254 is expressed.
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Protein Species
Rat
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Purity
>95% as determined by SDS-PAGE.
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Validations
Rat Csf1/Csfm recombinant protein
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