Rat CLM-9 / TREM4 (His Tag) recombinant protein

Rat CLM-9 / TREM4 (His Tag) recombinant protein

• DataSheet
• Material Safety Data Sheets (MSDS)

CLM-9, also known as TREM4, is a receptor which belongs to the TREM family. The TREM family of receptors regulates the activity of various cell types of the immune system including neutrophils, monocyte/macrophages, microglia, and dendritic cells. CLM-9 may mediate L-selectin-dependent lymphocyte rollings. It binds SELL in a calcium dependent manner. CLM-9 also binds lymphocyte which suggests that it functions in lymphocyte adhesion. The major CLM-9 transcript is expressed highly in human heart, skeletal muscle, and placenta. The mouse protein has been shown to be expressed in capillary endothelial cells. Human CLM-9 mediates the uptake of human IgA2 and mouse IgM.

CD300 ANTIGEN LIKE FAMILY MEMBER G; CD300 MOLECULE LIKE FAMILY MEMBER G; UNQ422/PRO846; CLM9; 2310016B05RIK; NEPMUCIN; CMRF-35-LIKE MOLECULE-9; CMRF35-LIKE MOLECULE 9; TRIGGERING RECEPTOR EXPRESSED ON MYELOID CELLS 4; CLM-9; RP23-398F7.7; CD300 ANTIGEN-LIKE FAMILY MEMBER G; TREM4; D11ERTD736E; TREM-4

Human Cells

A DNA sequence encoding the rat CD300LG (XP_002724611.1) (Met1-Arg160) was expressed with a polyhistidine tag at the C-terminus.

Rat

The recombinant rat CD300LG comprises 153 amino acids and predicts a molecular mass of 17.5 kDa. The apparent molecular mass of the recombinant protein is approximately 28 kDa in SDS-PAGE under reducing conditions.

> 95 % as determined by SDS-PAGE