Rat CD28 (Fc Tag) recombinant protein

Cat.#: 503526

Size:

Special Price 710.8 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Rat CD28 (Fc Tag) recombinant protein
  • Documents
  • Description
    CD28 (Cluster of Differentiation 28) is a disulphide-bonded glycoprotein belonging to the immunoglobulin (Ig) superfamily, and structurally consists of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. Mouse CD28 is constitutively expressed on the surface of all murine T cells and on developing thymocytes as disulfide-linked homodimers or as monomers. CD28 can binds the B7-1 and B7-2 ligand, and together perform important functions in the T and B cell response pathways. B7/CD28 family members, which can augment or antagonize T-cell receptor signaling, in the regulation of central and peripheral T-cell tolerance. CD28 is thus involved in T-cell activation, the induction of cell proliferation and cytokine production and promotion of T-cell survival.
  • Protein name
    CD28 antigen
  • Protein short names
    CH29-189K17.3; TP44; CD28; MGC138290
  • Uniprot ID
    G3V7C2
  • Gene Name
    Cd28; rCG_22337
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the rat Cd28 (EDL98926.1) (Met1-Lys149) was expressed with the Fc region of human IgG1 at the C-terminus.
  • Protein Species
    Rat
  • Molecular weight
    The recombinant rat Cd28 consists 371 amino acids and predicts a molecular mass of 42 kDa.
  • Purity
    > 90 % as determined by SDS-PAGE.
  • Validations

    Rat CD28 / TP44 Protein (Fc Tag)

    Rat CD28 / TP44 Protein (Fc Tag)

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"