NovoPro
Cart 2
  • Rat CCL5 recombinant protein (C-His)

Rat CCL5 recombinant protein (C-His)

Cat.#: 514742

Size:

Special Price 183.7 USD

Availability: In Stock
- +

Add to cart to get an online quotation

Product Information

  • Product Name
    Rat CCL5 recombinant protein (C-His)
  • Documents
  • Description
    Chemokines are a family of small chemotactic cytokines, or proteins secreted by cells. Chemokines share the same structure similarities such as small size, and the presence of four cysteine residues in conserved locations in order to form their 3-dimensional shape. Some of the chemokines are considered pro-inflammatory which can be induced to recruit cells of the immune system to a site of infection during an immune response, while others are considered homeostatic and are implied in controlling the migration of cells during normal processes of tissue maintenance and development. There are four members of the chemokine family: C-C kemokines, C kemokines, CXC kemokines and CX3C kemokines. The C-C kemokines have two cysteines nearby the amino terminus. There have been at least 27 distinct members of this subgroup reported for mammals, called C-C chemokine ligands-1 to 28. Chemokin ligand 5(CCL5) is chemotactic for T cells, basophils and eosinophils. Chemokin ligand 5(CCL5) has been considered a HIV-supressor secreted by CD8+ T cells and other immune cells. Chemokin ligand 5(CCL5) is a key to activating recruit leukocytes into inflammatory sites and in the presence of particular cytokines released by T cells, it can change the NK cells into CHAK cells.Immune Checkpoint Immunotherapy Cancer Immunotherapy Targeted Therapy
  • Protein name
    C-C motif chemokine 5
  • Uniprot ID
    P30882
  • Gene Name
    C-C motif chemokine 5; MuRantes; SIS-delta; Small-inducible cytokine A5; T-cell-specific protein RANTES
  • Source/Expression Host
    Yeast
  • Expression Plasmid/cDNA
    A DNA sequence encoding the rat CCL5 (NP_038681.2) (Ser25-Ser92) was expressed with a polyhistidine tag at the C-terminus.
  • Protein Species
    Rat
  • Molecular weight
    The recombinant rat CCL5 consists of 78 amino acids and predicts a molecular mass of 9.2 kDa.
  • Purity
    > 95 % as determined by SDS-PAGE.
  • Validations

    Rat CCL5/RANTES Protein 15472

    Rat CCL5/RANTES Protein 15472

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"