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  • Ranatuerin-2CHa peptide

Ranatuerin-2CHa peptide

Not For Human Use, Lab Use Only.

Cat.#: 300278

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* Buy 1 get 1 free (?) What is TFA?

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Product Information

  • Product Name
    Ranatuerin-2CHa peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    H-GLMDTVKNAAKNLAGQLLDRLKCKITGC-OH
  • Sequence
    H-Gly-Leu-Met-Asp-Thr-Val-Lys-Asn-Ala-Ala-Lys-Asn-Leu-Ala-Gly-Gln-Leu-Leu-Asp-Arg-Leu-Lys-Cys-Lys-Ile-Thr-Gly-Cys-OH (disulfide bond: Cys23-Cys28)
  • Length (aa)
    28
  • Peptide Purity (HPLC)
    95.04%
  • Molecular Formula
    C126H222N38O38S3
  • Molecular Weight
    2973.59
  • Source
    Synthetic
  • Form
    Powder
  • Description

    Ranatuerin-2CHa is an antimicrobial peptide originally isolated from the skin secretions of the Chiricahua leopard frog, Lithobates chiricahuensis. The peptide has a primary structure of GLMDTVKNAAKNLAGQLLDRLKCKITGC and contains a single disulfide bridge. It belongs to the ranatuerin-2 family of antimicrobial peptides, which are commonly found in skin secretions from New World ranid frogs.

    In antimicrobial assays, ranatuerin-2CHa displayed moderate growth-inhibitory activity against a range of microorganisms, including Escherichia coli, Staphylococcus aureus, Klebsiella pneumoniae, Pseudomonas aeruginosa, and Candida albicans, with minimum inhibitory concentrations ranging from 20 to 80 µM. The peptide also showed moderate hemolytic activity against human erythrocytes, with an LC50 value of 135 µM.

  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Conlon JM, Mechkarska M, Coquet L, et al. Characterization of antimicrobial peptides in skin secretions from discrete populations of Lithobates chiricahuensis (Ranidae) from central and southern Arizona. Peptides. 2011;32(4):664-9.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"