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  • RAGE antagonist peptide

RAGE antagonist peptide

Not For Human Use, Lab Use Only.

Cat.#: 319592

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* Buy 1 get 1 free (?) What is TFA?

Special Price 101.70 USD

Availability: 1-2 weeks
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Product Information

  • Product Name
    RAGE antagonist peptide
  • Documents

    Batch to batch variation of the purity

  • Sequence Shortening
    Acetylation-ELKVLMEKEL-NH2
  • Sequence
    Acetylation-Glu-Leu-Lys-Val-Leu-Met-Glu-Lys-Glu-Leu-NH2
  • Length (aa)
    10
  • Peptide Purity (HPLC)
    95.44%
  • Molecular Formula
    C57H101N13O17S
  • Molecular Weight
    1272.55
  • Source
    Synthetic
  • Form
    Powder
  • Description
    RAGE antagonist peptide binds to the receptor for advanced glycation end products (RAGE) and blocks its activation by multiple ligands, including S100P, S100A4, and HMGB-1.
  • Storage Guidelines
    Normally, this peptide will be delivered in lyophilized form and should be stored in a freezer at or below -20 °C. For more details, please refer to the manual: Handling and Storage of Synthetic Peptides
  • References
    • Arumugam T, Ramachandran V, Gomez SB, Schmidt AM, Logsdon CD. S100P-derived RAGE antagonistic peptide reduces tumor growth and metastasis. Clin Cancer Res. 2012 Aug 15;18(16):4356-64. doi: 10.1158/1078-0432.CCR-12-0221. Epub 2012 Jun 20. PMID: 22718861; PMCID: PMC3845828.
    • Yao L, Zhao H, Tang H, Liang J, Liu L, Dong H, Zou F, Cai S. The receptor for advanced glycation end products is required for β-catenin stabilization in a chemical-induced asthma model. Br J Pharmacol. 2016 Sep;173(17):2600-13. doi: 10.1111/bph.13539. Epub 2016 Jul 27. PMID: 27332707; PMCID: PMC4978160.
  • About TFA salt

    Trifluoroacetic acid (TFA) is a common counterion from the purification process using High-Performance Liquid Chromatography (HPLC). The presence of TFA can affect the peptide's net weight, appearance, and solubility.

    Impact on Net Weight: The TFA salt contributes to the total mass of the product. In most cases, the peptide content constitutes >80% of the total weight, with TFA accounting for the remainder.

    Solubility: TFA salts generally enhance the solubility of peptides in aqueous solutions.

    In Biological Assays: For most standard in vitro assays, the residual TFA levels do not cause interference. However, for highly sensitive cellular or biochemical studies, please be aware of its presence.

  • Molar Concentration Calculator

  • Dilution Calculator

  • Percent Concentration Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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• Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

• Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

• Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"