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Product Name
Recombinant RABP1 protein (His tag)
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Description
Recombinant Human Cellular Retinoic Acid-Binding Protein 1 (CRABP-I) Fragment (residues 1-137) is a high-purity, soluble protein designed for structural and biochemical studies. This fragment captures a stable, functional domain of CRABP-I, enabling research into retinoic acid regulation and signaling pathways.
Cellular retinoic acid-binding protein 1 (CRABP-I) is a cytosolic protein that plays a key role in regulating the access of retinoic acid to nuclear retinoic acid receptors, thereby influencing gene expression and cellular differentiation. Located in the cytoplasm, CRABP-I is essential for managing retinoic acid bioavailability and signaling, making it a critical component in studies of development, homeostasis, and disease mechanisms. The provided fragment (residues 1-137) represents a computationally optimized, stable region ideal for investigating protein function and interactions.
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Protein name
Cellular retinoic acid-binding protein 1
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Uniprot ID
P29762
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Gene Name
CRABP1; RBP5
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Source/Expression Host
E. coli
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Expression Plasmid/cDNA
DNA encoding 1-137 aa (P29762) were fused with C-terminal 6His tag.
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Sequence
MPNFAGTWKM RSSENFDELL KALGVNAMLR KVAVAAASKP HVEIRQDGDQ FYIKTSTTVR TTEINFKVGE GFEEETVDGR KCRSLATWEN ENKIHCTQTL LEGDGPKTYW TRELANDELI LTFGADDVVC TRIYVRELEH HHHHH
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Protein Species
Human
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Molecular weight
Predictes a molecular mass of 16.61 kDa. In SDS-PAGE under reducing conditions, it migrates as an approximately 17 kDa band.
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Purity
>90%, by SDS-PAGE with Coomassie Brilliant Blue staining.
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Activity
Not tested.
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Validations
Recombinant RABP1 protein (His tag) SDS-PAGE
M: Marker; Lane 1: RABP1; Lane 2: BSA
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"