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  • Px-Moricin peptide

Px-Moricin peptide

For research use only. We do not sell to patients.

Cat.#: 318778

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Optional Service: TFA RemovalWhat's this?

Special Price 367.4 USD

Availability: 5 weeks
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Product Information

  • Product Name
    Px-Moricin peptide
  • Documents
  • Quantity/Unit
    1 Vial
  • Sequence
    H-APKVNVNALKKGGRVIKKGLGVIGAAGTAHEVYNHVRNRNQG-Amidation
  • Three letter code
    H-Ala-Pro-Lys-Val-Asn-Val-Asn-Ala-Leu-Lys-Lys-Gly-Gly-Arg-Val-Ile-Lys-Lys-Gly-Leu-Gly-Val-Ile-Gly-Ala-Ala-Gly-Thr-Ala-His-Glu-Val-Tyr-Asn-His-Val-Arg-Asn-Arg-Asn-Gln-Gly-Amidation
  • Length (aa)
    42
  • Peptide Purity (HPLC)
    95.2
  • Molecular Formula
    C191H325N67O52
  • Molecular Weight
    4392.02
  • Source
    Synthetic
  • Additional Information
    Px-Moricin is a novel AMP moricin from diamondback moth (Plutella xylostella). Px-Mor exhibited a broad antimicrobial spectrum against Gram positive bacteria (GPB), Gram negative bacteria (GNB) and fungi. Moreover, scanning electron microscopy and transmission electron microscopy (TEM) revealed that Px-Mor can cause obvious morphological alterations in A. pullulans, which demonstrated its powerful effect on the mycelia growth inhibition. The relative expression levels of Px-Mor were highest in fourth instar and prepupa stage, suggesting that moricin played different roles at different developmental stages. Px-Mor may be mainly expressed in changeable period of metamorphosis of prepupa development, which illustrated that Moricin have certain biological significance during the process of metamorphosis.
  • Storage Guidelines
    Ideally Px-Moricin peptide should be stored in a freezer at or below -9C. Px-Moricin peptide should be refrigerated after reconstitution. For more details, please refer to the manual:Handling and Storage of Synthetic Peptides
  • References
    • Xu X, Zhong A, Wang Y, et al. Molecular Identification of a Moricin Family Antimicrobial Peptide (Px-Mor) From Plutella xylostella With Activities Against the Opportunistic Human Pathogen Aureobasidium pullulans. Front Microbiol. 2019
  • About TFA salt

    Trifluoroacetic acid (TFA) is a strong acid, which is commonly used to cleave synthesized peptides from solid-phase resins and is also used to improve HPLC performance in the peptide purification step. By default, custom peptides are delivered as lyophilized TFA salts, and can contain as much as 10-45% TFA.

    TFA in custom peptides can cause inexplicable discrepancies in subsequent assay data. For instance, TFA in nM concentrations has been shown to interfere with cellular assays, inhibiting cellular proliferation in some instances, and increasing cell viability in others . It has also been found to be an unintended allosteric modulator of the glycine receptor, GlyR.

    TFA Removal Service is recommended for:

    • Peptides that will be used in cellular assays
    • Peptides that will be used as APIs or in manufactured products
    • For hydrophilic peptides containing numerous basic residues

Peptide Services: NovoPro's peptide synthesis services include standard chemical peptide synthesis, peptide modification, peptide libraries, and recombinant peptide expression.

Standard Peptide Synthesis: NovoPro offers quality peptides at the most competitive prices in the industry, starting at $3.20 per amino acid. NovoPro provides PepBox – Automatic Quote Tool for online price calculation.

Peptide Modifications: NovoPro offers a wide range of peptide modification services including isotope labeling (2H, 15N, and 13C), multiple disulfide bonds, multiple phosphorylations, KLH, BSA, ovalbumin, amidation, acetylation, biotin, FITC, etc.

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"