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Cynomolgus PDGF-B/PDGF-2 (Fc Tag) recombinant protein

Cat.#: 502517

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Product Information

  • Product Name
    Cynomolgus PDGF-B/PDGF-2 (Fc Tag) recombinant protein
  • Documents
  • Protein name
    Putative uncharacterized protein
  • Uniprot ID
    G7PFK7
  • Gene Name
    EGM_02704
  • Source/Expression Host
    Human Cells
  • Expression Plasmid/cDNA
    A DNA sequence encoding the cynomolgus PDGFB (EHH65851.1) (Ser82-Thr190) was expressed with the Fc region of mouse IgG1 at the N-terminus.
  • Protein Species
    Cynomolgus
  • Molecular weight
    The recombinant cynomolgus PDGFB is a disulfide-linked homodimer. The reduced monomer comprises 345 amino acids and has a calculated molecular mass of 38.9 KDa. The apparent molecular mass of it is approximately 43 and 32 KDa in SDS-PAGE.
  • Purity
    > 95 % as determined by SDS-PAGE
  • Activity
    1. Measured in a cell proliferation assay using Balb/c 3T3 mouse embryonic fibroblasts. The ED50 for this effect is typically 5-25 ng/ml.
    2. Measured by its binding ability in a functional ELISA. Immobilized Cynomolgus PDGFRB-His (Cat:503982) at 10 μg/ml (100 μl/well) can bind Cynomolgus S4-mFc3-PDGFB, The EC50 of Cynomolgus S4-mFc3-PDGFB is 3.6-7.4 ng/ml.
  • Validations

    Cynomolgus PDGFB / PDGF-BB Protein (Fc Tag) SDS-PAGE

    Cynomolgus PDGFB / PDGF-BB Protein (Fc Tag) SDS-PAGE

Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"