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Product Name
PTPRU Polyclonal Antibody
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Description
Polyclonal antibody to PTPRU
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Tested applications
WB
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Species reactivity
Mouse, Rat
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Alternative names
PTPRU antibody; FMI antibody; PCP-2 antibody; PTP antibody; PTP-J antibody; PTP-PI antibody; PTP-RO antibody; PTPPSI antibody; PTPRO antibody; PTPU2 antibody; R-PTP-PSI antibody; R-PTP-U antibody; hPTP-J antibody; receptor-type tyrosine-protein phosphatase U antibody
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Isotype
Rabbit IgG
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Preparation
Antigen: Recombinant fusion protein containing a sequence corresponding to amino acids 1184-1433 of human PTPRU (NP_001181930.1).
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Clonality
Polyclonal
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Formulation
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
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Storage instructions
Store at -20℃. Avoid freeze / thaw cycles.
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Applications
WB 1:500 - 1:2000
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Validations
Western blot - PTPRU Polyclonal Antibody
Western blot analysis of extracts of rat brain, using PTPRU antibody at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit .Exposure time: 60s.
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Background
Tyrosine-protein phosphatase which dephosphorylates CTNNB1. Regulates CTNNB1 function both in cell adhesion and signaling. May function in cell proliferation and migration and play a role in the maintenance of epithelial integrity. May play a role in megakaryocytopoiesis.
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Please note: All products are "FOR RESEARCH USE ONLY AND ARE NOT INTENDED FOR DIAGNOSTIC OR THERAPEUTIC USE"